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Framework

EU

IVDR — Technical Documentation

The EU IVDR 2017/746 Technical Documentation requirements define the comprehensive documentation package that manufacturers must compile and maintain for in vitro diagnostic (IVD) medical devices. Covering Annexes II and III of the regulation, these requirements specify the device description, design and manufacturing information, safety and performance data, benefit-risk analysis, and product verification and validation evidence specific to IVD devices.

Overview

Background

Established under Regulation (EU) 2017/746, the In Vitro Diagnostic Medical Devices Regulation replaced the former IVD Directive (98/79/EC). The technical documentation requirements are substantially more detailed, reflecting the shift from a self-certification model for most IVDs to a risk-based classification system with greater notified body involvement and documentation scrutiny.

Applicability

These requirements apply to all manufacturers placing IVD medical devices on the EU market, regardless of device risk class. The technical documentation must demonstrate compliance with the General Safety and Performance Requirements and must be maintained throughout the device lifecycle. It is reviewed by notified bodies during conformity assessment for Class B, C, and D devices.

Core Principles

Device description and intended purpose
Design and manufacturing information
Safety and performance requirements evidence
Benefit-risk analysis for IVD devices
Analytical and clinical performance data
Product verification and validation
Post-market performance follow-up documentation
Labeling and instructions for use